More than sterilization. We deliver confidence.
Contract EO sterilization for medical devices
Siam Steri Services (SIS) is a 100% subsidiary of Tomoe Shokai, Japan, established in 2005. From our facility in Amata City Chonburi Industrial Estate we support customers throughout the sterilization lifecycle: validation, routine sterilization, aeration and residual gas testing.

Your product. Our expertise. One trusted sterilization partner.
- 21+years in Thailand
- 50+years of sterilization in the Tomoe group
- 8EO sterilization chambers
- 8pre-conditioning chambers
- 3international certifications
- 100%Tomoe Shokai subsidiary
Business scope
Two service lines under one roof, so you coordinate with a single sterilization partner.
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01Ethylene oxide (EO) sterilization services
Reliable, professional EO sterilization with dedicated pre-conditioning and sterilization facilities, supporting a wide range of medical devices and healthcare products.
- 8 pre-conditioning chambers
- 8 EO sterilization chambers
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02Laboratory: residual gas testing
Professional residual gas testing for EO-sterilized products in accordance with ISO 10993-7, for our sterilization customers and external customers alike. Our laboratory evaluates residual gases using the applicable test methods and customer requirements.
- Ethylene oxide (EO)
- Ethylene chlorohydrin (ECH)
- Ethylene glycol (EG)
Complete sterilization solutions
- Validation
- Routine sterilization
- Aeration
- Residual gas testing
One partner for the whole chain reduces the complexity of coordinating with multiple service providers.
EO line at a glance
- Pre-conditioning chambers
- 8
- EO sterilization chambers
- 8
- Usable chamber size
- 1.1 m wide, 1.8 m high, 6 m deep
- Pallets per cycle
- Up to 5 pallets of 1.1 x 1.3 m
How EO sterilization works
Ethylene oxide sterilizes at low temperature and without high pressure. It is effective against all types of microorganisms, does not corrode the product, and penetrates dry materials well.
Preconditioning
The product is brought to the right temperature and humidity in a preconditioning room so the gas acts evenly throughout the load.
Sterilization in a sealed vessel
Air is evacuated, EO gas is injected and held for a set time under controlled temperature, humidity and gas concentration.
Aeration
Some materials absorb the gas, so the product rests until the residual gas has dissipated and it is safe to use.
Products suited to EO sterilization
- Sensitive to heat or moisture
- Plastics, catheters, anesthesia equipment, electrical equipment
- Longer life when gas sterilized
- Rubber gloves, tubing, delicate surgical instruments
EOG sterilizer system flow
Every lot follows the same controlled path from receiving to dispatch.
Receiving and inspection
Products arrive at the warehouse and are transferred by forklift. Each lot is inspected for form, size, weight, quantity and lot number, and biological and chemical indicators (BI & CI) are placed.
Stage 1: Pre-conditioning chamber
Heated air circulation and clean steam bring the load to the required temperature and humidity.
Stage 2: Sterilization chamber
Pre-vacuum, humidification with clean steam, EO gas injection and controlled exposure. Exhaust gas passes through a scrubber.
Stage 3: Aeration room
Residual EO is removed from the products. Aeration air is treated by our biofilter before release.
Release and dispatch
BI & CI are determined, the lot is inspected again and dispatched to the customer.
BI: biological indicator · CI: chemical indicator
Why choose SIS
More than sterilization — we deliver confidence.
It is about building confidence that every process is effectively controlled and that every product is ready for safe and reliable use. Siam Steri Services is your trusted partner in EO sterilization, providing comprehensive services from validation and routine sterilization to aeration and residual gas testing.
Expertise you can trust
Our experienced team has strong expertise in EO sterilization and extensive experience handling a wide range of medical and healthcare products.
Quality and compliance
Our processes are controlled under a robust quality management system and applicable standards to ensure process quality, consistency and reliability.
Complete sterilization solutions
Validation → routine sterilization → aeration → residual gas testing, reducing the complexity of coordinating with multiple service providers.
Flexible solutions for your products
Every product is different. Our team works closely with customers to develop and adjust sterilization processes to specific product characteristics and requirements.
Reliable planning and on-time service
We place strong emphasis on capacity and schedule planning to support our customers' production plans and ensure reliable, on-time service.
Customer-centric partnership
We are more than a service provider: a partner who works closely with you to solve challenges, optimize processes and support your business throughout the sterilization journey.
About Siam Steri Services
Siam Steri Services Co., Ltd. was established in November 2005 as a 100% subsidiary of Tomoe Shokai Co., Ltd., Japan, to provide ethylene oxide gas sterilization for medical equipment. With expertise in EO sterilization, SIS provides a comprehensive service covering sterilization validation, routine sterilization and residual gas testing, supporting customers throughout the sterilization lifecycle.
- Established
- November 2005
- Shareholder
- Tomoe Shokai Co., Ltd., Japan (100%)
- Capital
- 425 million baht
- Head office and factory
- Amata City Chonburi Industrial Estate
SIS goals
- Expand service offering
- Obtain certification
- Continuous improvement
- Investment in technology
- Environmental care
- No. 1 in sterilization in Thailand
Tomoe overseas group
Our head office is in Japan, with overseas branches in India, China and across Southeast Asia: Singapore, Indonesia, Malaysia, Vietnam and the Philippines.
International standard certification
- ISO 13485:2016Medical devices: validation and routine control
- ISO 9001:2015Quality management system
- JPALJapanese Pharmaceutical Affairs Law
Company policy
We conduct our business with a strong commitment to quality and uphold it as a core principle throughout our operations.
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01
High standard of services
- High standard for sterilization
- Quick correspondence
- Strong relationship with customers
- High cost performance
- Innovative solutions
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02
Convenient location
- High-performance logistics
- Convenient access
- Extensive manufacturing area
- Strong overseas network
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03
Social contribution and compliance
- Compliance with safety and environmental regulations and standards
Quality policy
Siam Steri Services aims to be the most reliable sterilization service provider in terms of quality of service and compliance with customer and regulatory requirements.
Over 50 years of sterilization in the Tomoe group
- Tomoe Shokai Co., Ltd. established in Japan; begins sales of specialized gases
- Tomoe Shokai starts its sterilization business at the Omori plant, Japan
- Japan Gas Co., Ltd. Haneda sterilization plant starts
- Steril Services Thailand Co., Ltd. established
- Sterile Services Singapore established
- Siam Steri Services established in Chonburi, Thailand (November)
Corporate social responsibility
Environmental responsibility
Innovating for a cleaner environment
Biofilter project: innovative EO emission treatment
At SIS our responsibility goes beyond safe and reliable sterilization. We continuously improve our processes to reduce environmental impact and contribute to a more sustainable future. We are the world's first and only company to develop an environmentally responsible biofilter system for treating ethylene oxide (EO) emissions from the sterilization process before discharge.
How does it work?
- After EO sterilization, products are aerated so residual EO is removed from them.
- Air containing EO from the aeration process is directed through the biofilter before being discharged.
- Inside the biofilter, microorganisms break down EO and other biodegradable compounds, reducing the EO concentration in the treated air.
- Aeration air
- Biofilter
- Biological treatment
- Reduced EO concentration
- Air release
Our environmental commitment
Reducing EO emissions
Helping reduce the concentration of EO released from the aeration process.
Protecting the environment
Responsible control of emissions from our sterilization operations.
Applying innovative technology
Biological treatment technology as part of our environmental management approach.
Responsible sterilization operations
Environmental considerations integrated into our processes and facility operations.
Inside Siam Steri Services
Sample video: a short look at our facility, process and people.
Our facility

EO sterilization chambers 
Head office and factory, Amata City Chonburi 
Residual gas testing laboratory 
Our team
Contact us
Head office and factory, Chonburi
700/644 Moo 3, Amata City Chonburi Industrial EstateTambol Bankao, Amphur Panthong
Chonburi 20160, Thailand
Fax +66 38 447 022
Open mapAyutthaya branch
1/1 Moo 5, Rojana Industrial ParkKharn Harm, U-Thai
Ayutthaya 13210, Thailand
Tel +66 35 330 575
Fax +66 35 330 707
Open map